Minister for Business, Enterprise, and Innovation Heather Humphreys TD has announced the first winner of the SFI Future Innovator Prize, Dr Alison Liddy and her project team at NUI Galway.

Dr Liddy and the project team have been awarded €1million for their project, Hydrobloc, a novel and transformative treatment for people suffering from chronic pain.

Dr Alison Liddy, NUI Galway.

A special prize of €500,000 was also awarded to Prof Dominic Zerulla and his team at PEARlabs, University College Dublin (UCD), in recognition of the potential impact of their project to develop a novel, nanoscale biological imaging technology.

Cultivate challenge-based funding

The SFI Future Innovator Prize, funded by the Department of Business, Enterprise and Innovation through Science Foundation Ireland, is part of an overall government plan to cultivate challenge-based funding in Ireland.

This prize challenges the country’s best and brightest unconventional thinkers and innovators to create novel, potentially disruptive technologies in collaboration with societal stakeholders and end-users.

Minister Humphreys, TD, said: “Congratulations to the Hydrobloc team on winning this prestigious award and leading the way with this much needed novel and innovative treatment for chronic pain.”

Teams work to tight deadlines

The SFI Future Innovator Prize has a strong team focus with each member bringing necessary expertise to advance the project. Teams work to tight deadlines, with the necessary supports and flexibility, in order to accelerate progression towards their proposed solutions.

Professor Mark Ferguson, director general of Science Foundation Ireland and chief scientific adviser to the government said: “The SFI Future Innovator Prize is part of an approach to cultivate challenge-based funding in Ireland to accelerate and validate excellent and innovative solutions to critical societal and global issues.

"The Hydrobloc team headed by Dr Alison Liddy proved to be worthy first winners, successfully completing all aspects of this demanding and disruptive programme with the potential to alleviate chronic neuropathic pain with a novel nanogel.”

Chronic neuropathic pain sufferers live with constant pain, which has a significant personal and societal impact. Neuropathic pain is caused by damage or disease affecting the sensory nervous system (the part of the nervous system responsible for processing sensory information).  

It is estimated that 8% of the European population suffer from neuropathic pain, 300,000 in Ireland alone. The Hydrobloc nanogel (a nanogel is a tiny particle of submicroscopic size) provides long term pain relief which is drug free without the severe side effects of prescription medications.

On winning the final prize Dr Alison Liddy said:“The SFI Future Innovator Prize has been pivotal in allowing the Hydrobloc team at NUIG to significantly progress our research and realise its potential.

"We are honoured to win the final prize and have no doubt after being through the programme that there is a world-class level of innovative talent in Ireland which will benefit our country in the future.”

Significantly progress along patient pathway

The SFI Future Innovator Prize has enabled the Hydrobloc project to significantly progress along the patient pathway, further validate the clinical need among stakeholders, expand potential clinical indications, and develop and refine the core technology through extensive pre-clinical testing.

Asked about the experience of participating in the Future Innovator Prize programme, Dr Liddy added: “A unique aspect of the challenge programme is the social impact element which emphasised the societal aspects of our solution with crucial input not just from clinicians, but also from patients.

"By incorporating this Public and Patient Involvement (PPI) paradigm we have integrated the voice of the patient into Hydrobloc and ensured that the core goal is the development of a treatment that will improve the lives of patients living with debilitating pain.

"The programme has also introduced us to an exciting network of brilliantly innovative scientists and importantly has opened the door to investors.”